In collaboration with Pedro Beltrao, Ruedi Aebersold, Bernd Wollscheid, and an international consortium, we contributed to the creation of the first tissue-specific atlas of human protein–protein associations.

This large-scale effort integrates proteomics, genetics, and disease annotations to reveal how molecular networks vary across tissues, enabling the prioritization of candidate disease genes and context-dependent protein complex remodeling.

Published in Nature Biotechnology, the work demonstrates how systematic interactomics can bridge molecular networks and precision medicine.

Read the full paper: A tissue-specific atlas of protein–protein associations enables prioritization of candidate disease genes →